Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Letter
Nature Cell Biology 7, 901–908 (1 September 2005) | doi:10.1038/ncb1293
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization
&
Abstract
Growth of normal cells is anchorage dependent because signalling through multiple pathways including Erk, phosphatidylinositol-3-OH kinase (PI(3)K) and Rac requires integrin-mediated cell adhesion. Components of these pathways localize to low-density, cholesterol-rich domains in the plasma membrane named 'lipid rafts' or 'cholesterol-enriched membrane microdomains' (CEMM).
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
