Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Letter
Nature Cell Biology 7, 909–915 (1 September 2005) | doi:10.1038/ncb1291
Clusterin inhibits apoptosis by interacting with activated Bax
&
Abstract
Clusterin is an enigmatic glycoprotein that is overexpressed in several human cancers such as prostate and breast cancers, and squamous cell carcinoma. Because the suppression of clusterin expression renders human cancer cells sensitive to chemotherapeutic drug-mediated apoptosis, it is currently an antisense target in clinical trials for prostate cancer.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
