Brief Communication abstract
Nature Cell Biology 7, 916 - 917 (2005)
Published online: 1 September 2005 | doi:10.1038/ncb1295
Directionality of F-actin cables changes during the fission yeast cell cycle
Tomoko Kamasaki1,2,4, Ritsuko Arai1,5, Masako Osumi2,3 & Issei Mabuchi1
Longitudinal F-actin cables are thought to be important for transporting materials for polarized cell growth in fission yeast. We show that most F-actin in the cables is oriented such that the barbed end faces the nearest cell tip during interphase; however, this directionality is reversed during mitosis. These orientations of F-actin ensure proper transport of materials to growing sites during these cell-cycle stages.
- Division of Biology, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, 153-8902, Japan.
- Division of Material and Biological Function Sciences, Graduate School of Science, Japan Women's University, Tokyo, 112-8681, Japan.
- Instistute of Medical Mycology, Teikyo University, Tokyo, 192-0395, Japan.
- Present address: Department of Oral Histology, School of Dentistry, Showa University, Tokyo 142-8555, Japan.
- Present address: Department of Chemical Genetics, Riken, Wako, 351-0198, Japan.
Correspondence to: Issei Mabuchi1 e-mail: mabuchi@ims.u-tokyo.ac.jp
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