Nature Cell Biology
7, 858 - 859 (2005)
doi:10.1038/ncb0905-858
The hand that rocks the spindleChay T. Kuo
& Yuh-Nung Jan
Chay T. Kuo and Yuh-Nung Jan are at the Howard Hughes Medical Institute, Department of Physiology, University of California, San Francisco, 1550 4th Street, Room GD484E, San Francisco, CA 94143-0725, USA. ynjan@itsa.ucsf.edu
Asymmetric cell division is a fundamental process by which cells give rise to progenies with different fates. Although this mechanism is well studied in the worm and fly, mammalian asymmetric cell division is poorly understood. The finding that G  and AGS3 can control mitotic spindle orientation and progenitor cell fates during mouse cortical development suggests evolutionarily conserved roles in asymmetric cell division.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
