Suzanne Pfeffer is in the Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305-5307, USA. pfeffer@stanford.edu
The human genome encodes at least 70 Rab GTPases and more than 50 putative Rab GTPase-activating proteins (GAPs). An elegant scheme to rapidly identify the Rab target for each of these GAPs has led to the identification of a potent Rab GAP for Rab5.
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