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Nature Cell Biology 7, 779–781 (1 August 2005) | doi:10.1038/ncb0805-779

Cdk1: the dominant sibling of Cdk2

Tarig Bashir & Michele Pagano

The cell division cycle is a fundamental and highly complex process that lies at the core of every proliferating cell. Progression of the eukaryotic cell through four phases — G1, S, G2 and M — ensures that genetic information is first faithfully replicated (during S phase) and then equally distributed to two daughter cells (during M phase).