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RNAi and the P-body connection

Cytoplasmic processing bodies, also known as P-bodies, concentrate enzymes that are involved in mRNA turnover and sequester mRNAs away from the translational machinery. Strong evidence now connects the RNA interference machinery with P-body formation.

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Figure 1: A model for P-body assembly by RISC.

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Rossi, J. RNAi and the P-body connection. Nat Cell Biol 7, 643–644 (2005). https://doi.org/10.1038/ncb0705-643

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