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Letter
Nature Cell Biology 7, 619–625 (1 June 2005) | doi:10.1038/ncb1266
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia
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Abstract
Formins have important roles in the nucleation of actin and the formation of linear actin filaments, but their role in filopodium formation has remained elusive. Dictyostelium discoideum Diaphanous-related formin dDia2 is enriched at the tips of filopodia and interacts with profilin II and Rac1.
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