1. Paul R. Clarke is at the Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK. e-mail: paul.clarke@cancer.org.uk

Abstract

The small GTPase Ran controls nucleocytoplasmic transport and has multiple roles during cell division. A new study has identified the nuclear export factor Crm1 as a mitotic effector of Ran-GTP at kinetochores, where it has a role in microtubule attachment.

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