News and Views


Nature Cell Biology 7, 551 - 552 (2005)
doi:10.1038/ncb0605-551

The Crm de la crème of mitosis

Paul R. Clarke1

  1. Paul R. Clarke is at the Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK. e-mail: paul.clarke@cancer.org.uk


The small GTPase Ran controls nucleocytoplasmic transport and has multiple roles during cell division. A new study has identified the nuclear export factor Crm1 as a mitotic effector of Ran-GTP at kinetochores, where it has a role in microtubule attachment.

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