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Letter

Nature Cell Biology 7, 412–419 (1 April 2005) | doi:10.1038/ncb1239

SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions

Jordi Torres-Rosell , F|[eacute]|lix Mach|[iacute]|n , Sarah Farmer , Adam Jarmuz , Trevor Eydmann , Jacob Z. Dalgaard & Luis Arag|[oacute]|n

Structure chromosome (SMC) proteins organize the core of cohesin, condensin and Smc5–Smc6 complexes. The Smc5–Smc6 complex is required for DNA repair, as well as having another essential but enigmatic function.