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Letter
Nature Cell Biology 7, 399–404 (1 April 2005) | doi:10.1038/ncb1236
Regulation of PTEN by Rho small GTPases
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Abstract
PTEN (phosphatase and tensin homologue) is a phosphatase that dephosphorylates both protein and phosphoinositide substrates. It is mutated in a variety of human tumours and has important roles in a diverse range of biological processes, including cell migration and chemotaxis.
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