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Nature Cell Biology 7, 336–337 (1 April 2005) | doi:10.1038/ncb0405-336

Cell polarization mechanisms during directed cell migration

Anna Huttenlocher

Without a sense of direction, potential is often never realized. This is true of many cells that have the capacity to migrate towards or away from a diverse array of stimuli, but must first achieve direction through the establishment of cell polarity.