News and Views

Nature Cell Biology 7, 210 - 212 (2005)
doi:10.1038/ncb0305-210

An endocytic Prk-ing brake

Mara C. Duncan1 & Gregory S. Payne1

  1. Mara C. Duncan and Gregory S. Payne are at the Department of Biological Chemistry, David Geffen School of Medicine at UCLA, 33-257 CHS, Box 951737, Los Angeles, CA 90095-1737, USA. e-mail: gpayne@mednet.ucla.edu

Actin polymerization is intimately associated with endocytosis in yeast and mammalian cells. Mechanisms of actin filament assembly in endocytosis are becoming better understood but less is known about how assembly is terminated. In yeast, phosphorylation of Arp2/3 complex activators provides one mechanism for downregulating endocytic actin assembly.

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