News and Views
Nature Cell Biology 7, 1159 - 1161 (2005)
doi:10.1038/ncb1205-1059
There is an Erratum (December 2005) associated with this News and Views.
Receptor regulation: 
-arrestin moves up a notch
Sudha K. Shenoy1 & Robert J. Lefkowitz2
- Sudha K. Shenoy is in the Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
- Robert J. Lefkowitz is in the Howard Hughes Medical Institute, Department of Medicine and Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA. e-mail: lefko001@receptor-biol.duke.edu
Abstract
-arrestin, a protein known to regulate the signalling, trafficking and degradation of mammalian seven-transmembrane-spanning receptors, has now been identified as a regulator of ubiquitination and degradation of the Notch receptor in Drosophila melanogaster.
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