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Nature Cell Biology 7, 1047–1049 (1 November 2005) | doi:10.1038/ncb1105-1047

Drosophila G-protein signalling: intricate roles for Ric-8?

Fumio Matsuzaki

The generation of cell diversity relies heavily on asymmetric cell division, in which cell-fate determinants often cluster at specific locations — frequently at opposite poles of the parent cell. When the cell divides, its daughters inherit different sets of fate determinants and go on to adopt their respective identities.