News and Views
Nature Cell Biology 7, 1047 - 1049 (2005)
doi:10.1038/ncb1105-1047
Drosophila G-protein signalling: intricate roles for Ric-8?
Fumio Matsuzaki1
- Fumio Matsuzaki is at the Cell Asymmetry Group, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku Kobe 650-0047, Japan e-mail: fumio@cdb.riken.jp
Abstract
Receptor-independent G-protein signalling regulates both the orientation and position of the mitotic spindle during asymmetric cell division. Several new studies show that the targeting of G-protein subunits to the membrane requires Ric-8, pointing to possible novel roles for this protein in both receptor-dependent and -independent pathways.
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