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Letter
Nature Cell Biology 7, 985–992 (1 October 2005) | doi:10.1038/ncb1297
Genetic isolation of transport signals directing cell surface expression
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Abstract
Membrane proteins represent approximately 30% of the proteome in both prokaryotes and eukaryotes. The spatial localization of membrane-bound proteins is often determined by specific sequence motifs that may be regulated in response to physiological changes, such as protein interactions and receptor signalling.
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