Delayed impact - p925

doi:10.1038/ncb1005-925

Full Text - Delayed impact | PDF (102 KB) - Delayed impact

The heritage of cells - p926

Frank Sauer reviews Epigenetics and Chromatin by Philippe Jeanteur

doi:10.1038/ncb1005-926

Full Text - The heritage of cells | PDF (87 KB) - The heritage of cells

How and Y plant microtubules branch - pp927 - 929

Richard Cyr

doi:10.1038/ncb1005-927

Plant cortical microtubule arrays influence plant morphogenesis, but the nature of microtubule genesis and self-organization has long puzzled cell biologists. In this issue, Murata and coworkers provide some answers by showing that -tubulin nucleates new microtubules along the lengths of existing microtubules, resulting in dispersed 'Y'-branched organizational centres.

Full Text - How and Y plant microtubules branch | PDF (315 KB) - How and Y plant microtubules branch

See also: Letter by Murata et al.

More than a separase - pp930 - 932

Ethel Queralt & Frank Uhlmann

doi:10.1038/ncb1005-930

Anaphase onset is triggered when the protease separase cleaves the cohesive bond that holds replicated sister chromatids together until metaphase. In budding yeast, separase then also regulates mitotic exit. New findings suggest that in vertebrates, separase also participates in cell-cycle regulation, albeit in an unexpected manner.

Full Text - More than a separase | PDF (237 KB) - More than a separase

See also: Letter by Papi et al.

Tumorigenesis: TCF4 feeds c-Jun - p932

Myrto Raftopoulou

doi:10.1038/ncb1005-932

Full Text - Tumorigenesis: TCF4 feeds c-Jun | PDF (180 KB) - Tumorigenesis: TCF4 feeds c-Jun

Thieves, assassins and spies of the microbial world - pp933 - 934

Hera C. Vlamakis & Roberto Kolter

doi:10.1038/ncb1005-933

Extracellular signalling regulates a plethora of multicellular processes. For microbes, maintaining a specific cell–cell signal in an extracellular environment crowded by other species can be extremely challenging. Two recent papers demonstrate how different bacteria have adapted to avoid, or exploit, species cross-signalling.

Full Text - Thieves, assassins and spies of the microbial world | PDF (150 KB) - Thieves, assassins and spies of the microbial world

Fog shapes up myosin for gastrulation - p935

Alison Schuldt

doi:10.1038/ncb1005-935

Full Text - Fog shapes up myosin for gastrulation | PDF (282 KB) - Fog shapes up myosin for gastrulation

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome - pp937 - 946

Elena N. Pugacheva & Erica A. Golemis

doi:10.1038/ncb1309

Abstract - | Full Text - The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome | PDF (2,033 KB) - The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome | Supplementary information

The extracellular matrix guides the orientation of the cell division axis - pp947 - 953

Manuel Théry, Victor Racine, Anne Pépin, Matthieu Piel, Yong Chen, Jean-Baptiste Sibarita & Michel Bornens

doi:10.1038/ncb1307

First Paragraph - | Full Text - The extracellular matrix guides the orientation of the cell division axis | PDF (1,527 KB) - The extracellular matrix guides the orientation of the cell division axis | Supplementary information

ARHGAP10 is necessary for -catenin recruitment at adherens junctions and for Listeria invasion - pp954 - 960

Sandra Sousa, Didier Cabanes, Cristel Archambaud, Frédéric Colland, Emmanuel Lemichez, Michel Popoff, Stéphanie Boisson-Dupuis, Edith Gouin, Marc Lecuit, Pierre Legrain & Pascale Cossart

doi:10.1038/ncb1308

First Paragraph - | Full Text - ARHGAP10 is necessary for -catenin recruitment at adherens junctions and for Listeria invasion | PDF (1,754 KB) - ARHGAP10 is necessary for -catenin recruitment at adherens junctions and for Listeria invasion | Supplementary information

Microtubule-dependent microtubule nucleation based on recruitment of -tubulin in higher plants - pp961 - 968

Takashi Murata, Seiji Sonobe, Tobias I. Baskin, Susumu Hyodo, Seiichiro Hasezawa, Toshiyuki Nagata, Tetsuya Horio & Mitsuyasu Hasebe

doi:10.1038/ncb1306

First Paragraph - | Full Text - Microtubule-dependent microtubule nucleation based on recruitment of -tubulin in higher plants | PDF (1,510 KB) - Microtubule-dependent microtubule nucleation based on recruitment of -tubulin in higher plants | Supplementary information

See also: News and Views by Cyr

Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes - pp969 - 976

Metello Innocenti, Silke Gerboth, Klemens Rottner, Frank P. L. Lai, Maud Hertzog, Theresia E. B. Stradal, Emanuela Frittoli, Dominique Didry, Simona Polo, Andrea Disanza, Stefanie Benesch, Pier Paolo Di Fiore, Marie-France Carlier & Giorgio Scita

doi:10.1038/ncb1304

First Paragraph - | Full Text - Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes | PDF (1,123 KB) - Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes | Supplementary information

Abi activates WASP to promote sensory organ development - pp977 - 984

Sven Bogdan, Raiko Stephan, Christian Löbke, Alexandra Mertens & Christian Klämbt

doi:10.1038/ncb1305

First Paragraph - | Full Text - Abi activates WASP to promote sensory organ development | PDF (1,917 KB) - Abi activates WASP to promote sensory organ development | Supplementary information

Genetic isolation of transport signals directing cell surface expression - pp985 - 992

Sojin Shikano, Brian Coblitz, Haiyan Sun & Min Li

doi:10.1038/ncb1297

First Paragraph - | Full Text - Genetic isolation of transport signals directing cell surface expression | PDF (744 KB) - Genetic isolation of transport signals directing cell surface expression | Supplementary information

Ubx2 links the Cdc48 complex to ER-associated protein degradation - pp993 - 998

Oliver Neuber, Ernst Jarosch, Corinna Volkwein, Jan Walter & Thomas Sommer

doi:10.1038/ncb1298

First Paragraph - | Full Text - Ubx2 links the Cdc48 complex to ER-associated protein degradation | PDF (455 KB) - Ubx2 links the Cdc48 complex to ER-associated protein degradation | Supplementary information

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation - pp999 - 1006

Christian Schuberth & Alexander Buchberger

doi:10.1038/ncb1299

First Paragraph - | Full Text - Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation | PDF (524 KB) - Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation | Supplementary information

Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin - pp1007 - 1013

Songtao Jia, Ryuji Kobayashi & Shiv I. S. Grewal

doi:10.1038/ncb1300

First Paragraph - | Full Text - Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin | PDF (704 KB) - Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin | Supplementary information

Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation - pp1014 - 1020

June-Tai Wu, Hsiu-Chen Lin, Yen-Chen Hu & Cheng-Ting Chien

doi:10.1038/ncb1301

First Paragraph - | Full Text - Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation | PDF (2,567 KB) - Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation | Supplementary information

The endoplasmic reticulum gateway to apoptosis by Bcl-X_L modulation of the InsP₃R - pp1021 - 1028

Carl White, Chi Li, Jun Yang, Nataliya B. Petrenko, Muniswamy Madesh, Craig B. Thompson & J. Kevin Foskett

doi:10.1038/ncb1302

First Paragraph - | Full Text - The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R | PDF (959 KB) - The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R | Supplementary information

Multiple roles for separase auto-cleavage during the G2/M transition - pp1029 - 1035

Maura Papi, Eli Berdougo, Catherine L. Randall, Sonali Ganguly & Prasad V. Jallepalli

doi:10.1038/ncb1303

First Paragraph - | Full Text - Multiple roles for separase auto-cleavage during the G2/M transition | PDF (808 KB) - Multiple roles for separase auto-cleavage during the G2/M transition | Supplementary information

See also: News and Views by Queralt & Uhlmann

Addendum - p1036

doi:10.1038/ncb1310

Full Text - Addendum | PDF (50 KB) - Addendum