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Letter
Nature Cell Biology 7, 1021–1028 (1 October 2005) | doi:10.1038/ncb1302
The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R
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Abstract
Members of the Bcl-2 protein family modulate outer mitochondrial membrane permeability to control apoptosis. However, these proteins also localize to the endoplasmic reticulum (ER), the functional significance of which is controversial.
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