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Letter

Nature Cell Biology 7, 56–62 (1 January 2005) | doi:10.1038/ncb1203

A critical role for Cyclin E in cell fate determination in the central nervous system of Drosophila melanogaster

Christian Berger , S. K. Pallavi , Mohit Prasad , L. S. Shashidhara & Gerhard M. Technau

We have examined the process by which cell diversity is generated in neuroblast (NB) lineages in the central nervous system of Drosophila melanogaster. Thoracic NB6-4 (NB6-4t) generates both neurons and glial cells, whereas NB6-4a generates only glial cells in abdominal segments.