News and Views
Nature Cell Biology 7, 8 - 9 (2005)
doi:10.1038/ncb0105-8
A phosphatase for cofilin to be HAD
O'Neil Wiggan1, Barbara W. Bernstein1 & James R. Bamburg1
- O'Neil Wiggan, Barbara W. Bernstein and James R. Bamburg are in the Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA. e-mail: jbamburg@lamar.colostate.edu
Abstract
Regulating actin dynamics through cofilin dephosphorylation is the role of a newly identified phosphatase, chronophin, a member of the haloacid dehalogenase (HAD) superfamily. Chronophin, the second cofilin phosphatase to be identified, has high phosphoprotein specificity towards cofilin, but curiously it was also discovered independently as a pyridoxal phosphate (vitamin B6) phosphatase.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamicsNature Cell Biology Article (01 Jan 2005)
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilinThe EMBO Journal Article (03 Oct 2007)
MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migrationThe EMBO Journal Article (22 Feb 2006)
Interplay between components of a novel LIM kinase?slingshot phosphatase complex regulates cofilinThe EMBO Journal Article (09 Feb 2005)
See all 8 matches for Research
