M. Andrew Hoyt is in the Department of Biology, The Johns Hopkins University, 3400 North Charles St., Baltimore, MD 21218, USA. hoyt@jhu.edu
Cell duplication requires the coordination of nuclear division with diverse cellular morphogenesis events, such as cell wall growth. A novel checkpoint has been identified in yeast that coordinates these two events. Unexpectedly, the dynein-activating dynactin complex, but not dynein itself, is an essential component of this checkpoint mechanism.
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