News and Views
Nature Cell Biology 6, 693 - 695 (2004)
doi:10.1038/ncb0804-693
Developmental quiescence: Cdc14 moonlighting in G1
Edward T. Kipreos1
- Edward T. Kipreos is at the Department of Cellular Biology, University of Georgia, Athens, GA 30602-2607, USA. e-mail: ekipreos@cb.uga.edu
Abstract
Cdc14 is a phosphatase that can antagonize CDK/cyclin cell-cycle functions. New insights from Caenorhabditis elegans show that CDC-14 is required to prevent cell-cycle entry during extended periods of developmentally regulated quiescence, and also clarify its role in creating the central mitotic spindle during anaphase.
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