News and Views
Nature Cell Biology 6, 690 - 692 (2004)
doi:10.1038/ncb0804-690
Exciting trips for TRPs
Craig Montell1
- Craig Montell is at the Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. e-mail: cmontell@jhmi.edu
Abstract
A potentially common, but poorly understood, mode of activation for the TRP family of cation channels is regulated translocation of the protein to the plasma membrane. The pathway underlying exocytosis of TRPC5 has now been outlined and demonstrates its importance for modulating neurite extension.
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