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Letter
Nature Cell Biology 6, 656–664 (1 July 2004) | doi:10.1038/ncb1146
Centriolar SAS-5 is required for centrosome duplication in C. elegans
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Abstract
Centrosomes, the major microtubule-organizing centres (MTOCs) of animal cells, are comprised of a pair of centrioles surrounded by pericentriolar material (PCM). Early in the cell cycle, there is a single centrosome, which duplicates during S-phase to direct bipolar spindle assembly during mitosis.
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