1. Erika L. F. Holzbaur is at the University of Pennsylvania School of Medicine, D400 Richards Building, 3700 Hamilton Walk, Philadelphia, PA 19104-6085, USA. e-mail: holzbaur@mail.med.upenn.edu

Abstract

NUDEL was first identified as a protein required for nuclear migration in filamentous fungi. Now, a study shows that it is important for normal assembly of neurofilaments in the mammalian nervous system. In utero knockdown of NUDEL expression results in disruption of neurofilament organization.

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