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Letter

Nature Cell Biology 6, 555–562 (1 June 2004) | doi:10.1038/ncb1135

Cohesin SMC1|[beta]| is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination

Ekaterina Revenkova , Maureen Eijpe , Christa Heyting , Craig A. Hodges , Patricia A. Hunt , Bodo Liebe , Harry Scherthan & Rolf Jessberger

Sister chromatid cohesion ensures the faithful segregation of chromosomes in mitosis and in both meiotic divisions. Meiosis-specific components of the cohesin complex, including the recently described SMC1 isoform SMC1β, were suggested to be required for meiotic sister chromatid cohesion and DNA recombination.