News and Views

Nature Cell Biology 6, 384 - 385 (2004)
doi:10.1038/ncb0504-384

New candidates for vesicle coat proteins

Michael Roth1

  1. Michael Roth is in the University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA. e-mail: michael.roth@utsouthwestern.edu

Proteins exit the trans-Golgi network (TGN) through multiple mechanisms that are poorly understood. New work identifies FAPP1 and FAPP2 as TGN-localized proteins that regulate post-Golgi carrier formation through interactions with phosphatidylinositol 4-phosphate (PtdIns(4)P) and ARF1.

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