1. Temporary address: John Pearson and Acaimo González-Reyes are in the Instituto de Parasitología y Biomedicina-CSIC, C/Ventanilla 11, 18001 Granada, Spain. Permanent address: Centro Andaluz de Biología del Desarrollo (CSIC-UPO), Universidad 'Pablo de Olavide', Carretera de Utrera Km 1, 41013 Sevilla, Spain. e-mail: agr@ipb.csic.es

Abstract

The specificity of cytoskeleton-mediated cargo transport is critical for cell polarization. The Egalitarian protein — required for the localization of mRNAs and proteins to the oocyte of the Drosophila melanogaster ovary — is now reported to interact with an integral component of the dynein motor complex, the dynein light chain Dlc1.

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