1. Sue Biggins is in the Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
   e-mail: sbiggins@fhcrc.org

Abstract

The remarkable fidelity of chromosome segregation during mitosis and meiosis is critical for preventing birth defects and diseases. The Aurora protein kinases prevent defects in segregation by correcting mistakes in chromosome attachment to the spindle before cells divide.

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