A physical and functional map of the human TNF-/NF-B signal transduction pathwaypp97 - 105 Tewis Bouwmeester, Angela Bauch, Heinz Ruffner, Pierre-Olivier Angrand, Giovanna Bergamini, Karen Croughton, Cristina Cruciat, Dirk Eberhard, Julien Gagneur, Sonja Ghidelli, Carsten Hopf, Bettina Huhse, Raffaella Mangano, Anne-Marie Michon, Markus Schirle, Judith Schlegl, Markus Schwab, Martin A. Stein, Andreas Bauer, Georg Casari, Gerard Drewes, Anne-Claude Gavin, David B. Jackson, Gerard Joberty, Gitte Neubauer, Jens Rick, Bernhard Kuster
& Giulio Superti-Furga Published online: 25 January 2004|doi:10.1038/ncb1086 Abstract|Full text|PDF
(992K)
|Supplementary Information See also:News and Views by Hayden & Ghosh
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi networkpp106 - 112 Charles Yeaman, M. Inmaculada Ayala, Jessica R. Wright, Frederic Bard, Carine Bossard, Agnes Ang, Yusuke Maeda, Thomas Seufferlein, Ira Mellman, W. James Nelson
& Vivek Malhotra Published online: 25 January 2004|doi:10.1038/ncb1090 Abstract|Full text|PDF
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A novel mechanism for the store-operated calcium influx pathwaypp113 - 120 Tarik Smani, Sergey I. Zakharov, Peter Csutora, Endri Leno, Elena S. Trepakova
& Victoria M. Bolotina Published online: 18 January 2004|doi:10.1038/ncb1089 Abstract|Full text|PDF
(394K)
|Supplementary Information
ASC is a Bax adaptor and regulates the p53−Bax mitochondrial apoptosis pathwaypp121 - 128 Takao Ohtsuka, Hoon Ryu, Yohji A. Minamishima, Salvador Macip, Junji Sagara, Keiichi I. Nakayama, Stuart A. Aaronson
& Sam W. Lee Published online: 18 January 2004|doi:10.1038/ncb1087 Abstract|Full text|PDF
(684K)
|Supplementary Information
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC−Cdc20 complexpp129 - 137 Min Sup Song, Su Jeong Song, Nagi G. Ayad, Jin Sook Chang, Joo Hyun Lee, Hyun Kyung Hong, Ho Lee, Naeyun Choi, Jhingook Kim, Hojoong Kim, Jin Woo Kim, Eui-Ju Choi, Marc W. Kirschner
& Dae-Sik Lim Published online: 25 January 2004|doi:10.1038/ncb1091 Abstract|Full text|PDF
(890K)
|Supplementary Information
The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progressionpp138 - 145 Jennifer S. Searle, Kaila L. Schollaert, Benjamin J. Wilkins
& Yolanda Sanchez Published online: 25 January 2004|doi:10.1038/ncb1092 Abstract|Full text|PDF
(2,186K)
|Supplementary Information
Gadd45 mediates the NF-B suppression of JNK signalling by targeting MKK7/JNKK2pp146 - 153 Salvatore Papa, Francesca Zazzeroni, Concetta Bubici, Shanthi Jayawardena, Kellean Alvarez, Shuji Matsuda, Dung U. Nguyen, Can G. Pham, Andreas H. Nelsbach, Tiziana Melis, Enrico De Smaele, Wei-Jen Tang, Luciano D'Adamio
& Guido Franzoso Published online: 25 January 2004|doi:10.1038/ncb1093 Abstract|Full text|PDF
(823K)
|Supplementary Information
FAK−Src signalling through paxillin, ERK and MLCK regulates adhesion disassemblypp154 - 161 Donna J. Webb, Karen Donais, Leanna A. Whitmore, Sheila M. Thomas, Christopher E. Turner, J. Thomas Parsons
& Alan F. Horwitz Published online: 25 January 2004|doi:10.1038/ncb1094 Abstract|Full text|PDF
(462K)
|Supplementary Information
Modulation of heat shock gene expression by the TAC1 chromatin-modifying complexpp162 - 167 Sheryl T. Smith, Svetlana Petruk, Yurii Sedkov, Elizabeth Cho, Sergei Tillib, Eli Canaani
& Alexander Mazo Published online: 18 January 2004|doi:10.1038/ncb1088 Abstract|Full text|PDF
(446K)
See also:News and Views by Sanchez-Elsner & Sauer
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breakspp168 - 170 Olga A. Sedelnikova, Izumi Horikawa, Drazen B. Zimonjic, Nicholas C. Popescu, William M. Bonner
& J. Carl Barrett Published online: 02 February 2004|doi:10.1038/ncb1095 Abstract|Full text|PDF
(458K)
|Supplementary Information
/NF-
B signal transduction pathway
mediates the NF-
