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Letter
Nature Cell Biology 6, 991–996 (1 October 2004) | doi:10.1038/ncb1177
Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex
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Abstract
Cohesin is a multi-subunit, ring-shaped protein complex that holds sister chromatids together from the time of their synthesis in S phase until they are segregated in anaphase. In yeast, the loading of cohesin onto chromosomes requires the Scc2 protein.
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