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Letter
Nature Cell Biology 6, 38–44 (1 January 2004) | doi:10.1038/ncb1082
The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling
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Abstract
Fibroblast growth factors (FGFs) signal through high-affinity tyrosine kinase receptors to regulate a diverse range of cellular processes, including cell growth, differentiation and migration, as well as cell death. Here we identify XFLRT3, a member of a leucine-rich-repeat transmembrane protein family, as a novel modulator of FGF signalling.
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