1. Amy Shaub Maddox and Karen Oegema are in the Ludwig Institute for Cancer Research, University of California, San Diego, CMM-East 3080, 9500 Gilman Drive, La Jolla, CA 92093, USA.
   e-mail: koegema@ucsd.edu or e-mail: amaddox@ucsd.edu

Abstract

In animal cells, cytokinesis is initiated by assembly and ingression of a cleavage furrow, the position of which is determined by signals from the anaphase spindle. Recent work highlights two specialized microtubule populations that may stimulate furrow assembly: inter-zonal microtubule bundles, and astral microtubules that are stabilized by proximity to chromosomes.

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