Supplementary information

From the following article

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Erik Sahai & Christopher J. Marshall

Nature Cell Biology 5, 711 - 719 (2003) Published online: 6 July 2003

doi:10.1038/ncb1019

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Supplementary Information, Fig. S1

Movie 1. Time-lapse movie of GFP-A375m2 cells moving in 3D Matrigel, the first part of the movie shows a 360 rotation around the cells at a fixed timepoint before animation through the timepoints (timepoints are 450s apart).

Movie 2. Time-lapse movie of GFP-A375m2 cells moving in 3D Matrigel, the movie shows a single confocal section (timepoints are 30 minutes apart).

Movie 3. Time-lapse movie of A375m2 cells on 2D tissue culture plastic in 10%DCS (timepoints are 5 minutes apart).

Movie 4. Time-lapse movie of A375m2 cells on 2D tissue culture plastic in 10%DCS treated with 10microm Y27632 five hours prior to filming (timepoints are 5 minutes apart).

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