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Letter

Nature Cell Biology 5, 727–732 (1 August 2003) | doi:10.1038/ncb1025

Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs

Anna Marie Sokac , Carl Co , Jack Taunton & William Bement

The actin filament (F-actin) cytoskeleton associates dynamically with the plasma membrane and is thus ideally positioned to participate in endocytosis. Indeed, a wealth of genetic and biochemical evidence has confirmed that actin interacts with components of the endocytic machinery, although its precise function in endocytosis remains unclear.