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Nature Cell Biology 5, 589–590 (1 July 2003) | doi:10.1038/ncb0703-589
Movin' on through with Cdc2
Abstract
The ability of malignant tumours to invade surrounding tissues requires that the tumour cells be motile. Cell motility involves a highly complex spatiotemporally orchestrated series of events that includes extension of a membrane protrusion, formation of stable cell–matrix attachments near the leading edge of the protrusion, movement of the cell body forwards, and release and retraction at the rear of the cell.
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