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Nature Cell Biology 5, 493–495 (1 June 2003) | doi:10.1038/ncb0603-493

The return of the exocyst

Casper C. Hoogenraad & Morgan Sheng

Neurons communicate with each other through specialized cell junctions called synapses. In excitatory synapses of the mammalian brain, synaptic transmission is initiated through release of a neurotransmitter (usually glutamate) from the presynaptic cell.