About the cover
June 2003 Volume 5 No 6
Drosophila melanogaster Rheb, a small GTPase that functions in the insulin/TOR pathway, promotes cell growth. The image shows fat-body (adipose) tissue from a Drosophila larva in which Rheb was overexpressed in the cells that are marked green with green fluorescent protein (GFP). Blue indicates DNA, and dark areas within the cells are lipid vesicles. This tissue was taken from a larva that had been starved of dietary protein for three days before analysis, a treatment that
normally blocks the growth of fat-body cells. Cells over-expressing Rheb continue to grow despite the starvation regime.
Cover design: James McQuat
Cover design: James McQuat
