News and Views
Nature Cell Biology 5, 499 - 501 (2003)
doi:10.1038/ncb0603-499
Deconstructing phosphatases in limb development
Andrew T. Dudley1 & Clifford J. Tabin1
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Andrew T. Dudley and Clifford J. Tabin are in the Harvard Medical School, Department of Genetics, 200 Longwood Avenue, Boston, MA 02115, USA.
e-mail: tabin@rascal.med.harvard.edu
Abstract
Signalling by growth factors, such as fibroblast growth factor (FGF), is critical for many of the morphogenetic events that shape the early embryo — including limb development. Recent findings regarding the regulation of FGF during limb development bridge the divide between results gained from in vitro biochemistry and the realities of in vivo development.
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