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Nature Cell Biology 5, 379 - 382 (2003)
doi:10.1038/ncb0503-379

Monopolar attachment by Polo

Yoshinori Watanabe1

  1. Yoshinori Watanabe is at the Department of Biophysics and Biochemistry, Graduate School of Science, SORST, Japan Science Technology Corporation, University of Tokyo, Hongo, Tokyo 113-0033, Japan.
    e-mail: ywatanab@ims.u-tokyo.ac.jp.

A distinguishing feature of meiosis is a reductional division where homologous chromosomes — rather than sister chromatids — are pulled to opposite poles. Polo-like kinase (Plk), a prominent regulator of mitotic progression in Saccharomyces cerevisiae, is also crucial in regulating chromosome and chromatid separation during meiosis.

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