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Nature Cell Biology 5, 278–280 (1 April 2003) | doi:10.1038/ncb0403-278

Anti-silencing from the core: a histone H2A variant protects euchromatin

Marc Hild & Renato Paro

Early cytological studies defined euchromatin and heterochromatin as two differentially stained portions of nuclear chromatin. Subsequent work has identified a multitude of additional structural and functional features that characterize these two forms.