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Nature Cell Biology 5, 281 - 283 (2003)
doi:10.1038/ncb0403-281
A retention factor keeps death at bay
Steven F. Nothwehr1 & Jean-Claude Martinou2
- Steven F. Nothwehr is in the Division of Biological Sciences, University of Missouri, Columbia, 65211 MO, USA.
- Jean-Claude Martinou is in the Department of Cell Biology, University of Geneva,Quai Ernest-Ansermet 30, CH1211 - Geneva 4, Geneva, Switzerland.
Correspondence to: Jean-Claude Martinou2 e-mail: jean-claude.martinou@cellbio.unige.ch
Abstract
Apoptosis is a carefully orchestrated series of events that allows cells to be eliminated without damaging their neighbours. Regulation is essential, as too much apoptosis can contribute to neurodegenerative disorders, whereas too little can result in cancer. Two reports in this issue now demonstrate that Ku70, a protein previously shown to function in DNA repair, has an important role in regulating apoptotic events.
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