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Nature Cell Biology 5, 188–190 (1 March 2003) | doi:10.1038/ncb0303-188
Multitasking at mitotic exit
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Abstract
When cells are poised to complete mitosis, much of the hard work has already been done: the chromosomes have been replicated and neatly compacted, the spindle pole has been duplicated, all chromosomes have been attached to the spindle microtubules in a bipolar fashion and the site of the future cleavage furrow has been defined. To complete the cell cycle, all that remains is the tricky task of segregating the sister chromatids and then dividing, in that order; otherwise catastrophic consequences will ensue.
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