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Nature Cell Biology  5, 91 - 92 (2003)
doi:10.1038/ncb0203-102

Killer wiles: growing interest in Fas

Brigitte Pettmann & Christopher E. Henderson

Chris Henderson and Brigitte Pettmann are at the Developmental Biology Institute of Marseille (IBDM; CIIRS, INSERM) Campus de Luminy - Case 907 13288 Marseille Cedex 09, France
chris@ibdm.univ-mrs.fr

Signalling pathways involved in axonal growth are the subject of intense study. A new report further highlights the role of the extracellular signal-regulated kinase (ERK)/p35 pathway, but identifies a surprising potential trigger: the death receptor Fas. This study illustrates the importance of cellular context in the functional outcome of a given signalling mechanism.

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RESEARCH
Fas engagement induces neurite growth through ERK activation and p35 upregulation
Nature Cell Biology Article (01 Feb 2003)

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Nature Cell Biology
ISSN: 1465-7392
EISSN: 1476-4679
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