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Letter

Nature Cell Biology 5, 1079–1082 (1 December 2003) | doi:10.1038/ncb1067

Alternate fast and slow stepping of a heterodimeric kinesin molecule

Kuniyoshi Kaseda , Hideo Higuchi & Keiko Hirose

A conventional kinesin molecule travels continuously along a microtubule in discrete 8-nm steps. This processive movement is generally explained by models in which the two identical heads of a kinesin move in a 'hand-over-hand' manner.