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Letter
Nature Cell Biology 5, 1095–1103 (1 December 2003) | doi:10.1038/ncb1065
RGS16 inhibits signalling through the G|[alpha]|13|[ndash]|Rho axis
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Abstract
Gα13 stimulates the guanine nucleotide exchange factors (GEFs) for Rho, such as p115Rho-GEF. Activated Rho induces numerous cellular responses, including actin polymerization, serum response element (SRE)-dependent gene transcription and transformation.
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