Table of contents
November 2003, Volume 5 No 11 pp937-1025
About the coverEditorial
NCB demography – democracy? - p937
doi:10.1038/ncb1103-937
Full Text - NCB demography – democracy? | PDF (58 KB) - NCB demography – democracy?
Perspective
The case for morphogens in plants - pp939 - 943
Rishikesh P. Bhalerao & Malcolm J. Bennett
doi:10.1038/ncb1103-939
Abstract - | Full Text - The case for morphogens in plants | PDF (211 KB) - The case for morphogens in plants
Book Review
What is lost in translation? - p944
Henry R. Bourne reviews Signal Transduction and Human Disease by Toren Finkel & J. Silvio Gutkind
doi:10.1038/ncb1103-944
Full Text - What is lost in translation? | PDF (85 KB) - What is lost in translation?
News and Views
The kinetochore NUPtials - pp945 - 947
P. Todd Stukenberg & Ian G. Macara
doi:10.1038/ncb1103-945
The most interesting discoveries are often those that couple distinct fields of science in unexpected ways. The marriage of the nuclear pore complex to the kinetochore and spindle checkpoint regulation is a recent example, raising the question of why such divergent processes as mitosis and nuclear transport use common proteins.
Full Text - The kinetochore NUPtials | PDF (157 KB) - The kinetochore NUPtials
Architects of the chromosome - p947
Donald McDonald
doi:10.1038/ncb1103-947
Full Text - Architects of the chromosome | PDF (101 KB) - Architects of the chromosome
Stuck without Traffic Jam - pp948 - 949
Helen McNeill
doi:10.1038/ncb1103-948
During organogenesis different cells must recognize and adhere to each other in a complicated orchestration of cell movements that requires intricate regulation of cell adhesions. A Maf transcription factor, Traffic jam, has been found to regulate a panel of cell adhesion molecules, and the interactions between germ cells and somatic cells to shape the mature gonad.
Full Text - Stuck without Traffic Jam | PDF (129 KB) - Stuck without Traffic Jam
BTB proteins as henchmen of Cul3-based ubiquitin ligases - pp950 - 951
Wilhelm Krek
doi:10.1038/ncb1103-950
The choice of ubiquitination substrates of Cul1- and Cul2-based E3 ubiquitin protein ligase complexes is dictated by the identity of their substrate-specific adaptors, known as F-box and BC-box proteins, respectively. Recent work suggests that members of the large family of BTB-domain proteins define a new class of substrate-specific adaptors of Cul3-based E3 complexes. This finding places many signalling pathways in which BTB-domain proteins participate under direct control of the ubiquitination pathway.
Full Text - BTB proteins as henchmen of Cul3-based ubiquitin ligases | PDF (121 KB) - BTB proteins as henchmen of Cul3-based ubiquitin ligases
Stem cell fusion in the brain - pp952 - 954
Yevgenia Kozorovitskiy & Elizabeth Gould
doi:10.1038/ncb1103-952
Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.
Full Text - Stem cell fusion in the brain | PDF (164 KB) - Stem cell fusion in the brain
Plant microtubule nucleation sites: moving right along - p954
Sue Wick
doi:10.1038/ncb1103-954
Full Text - Plant microtubule nucleation sites: moving right along | PDF (102 KB) - Plant microtubule nucleation sites: moving right along
Three Yips for Rab recruitment - pp955 - 956
Jemima Barrowman & Peter Novick
doi:10.1038/ncb1103-955
Rab GTPases function at all stages of the endocytic and exocytic pathways. Although it is clear that each Rab is required for specific transport events, the process by which they are recruited to distinct compartments along the membrane trafficking pathway has remained obscure. Recent data suggests that a member of the Yip family is important for the membrane recruitment of endosomal Rabs.
Full Text - Three Yips for Rab recruitment | PDF (112 KB) - Three Yips for Rab recruitment
Cell of the month: An insect blood cell engulfing bacteria - p957
Paul Dean
doi:10.1038/ncb1103-957
Full Text - Cell of the month: An insect blood cell engulfing bacteria | PDF (212 KB) - Cell of the month: An insect blood cell engulfing bacteria
Article
Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant - pp959 - 966
James M. Weimann, Clas B. Johansson, Angelica Trejo & Helen M. Blau
doi:10.1038/ncb1053
Abstract - | Full Text - Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant | PDF (1,371 KB) - Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant
See also: News and Views by Kozorovitskiy & Gould
Letters
EB1 reveals mobile microtubule nucleation sites in Arabidopsis - pp967 - 971
Jordi Chan, Grant M. Calder, John H. Doonan & Clive W. Lloyd
doi:10.1038/ncb1057
First Paragraph - | Full Text - EB1 reveals mobile microtubule nucleation sites in Arabidopsis | PDF (605 KB) - EB1 reveals mobile microtubule nucleation sites in Arabidopsis | Supplementary information
See also: News and Views by Wick
Actin filament uncapping localizes to ruffling lamellae and rocketing vesicles - pp972 - 979
Philip G. Allen
doi:10.1038/ncb1059
First Paragraph - | Full Text - Actin filament uncapping localizes to ruffling lamellae and rocketing vesicles | PDF (1,991 KB) - Actin filament uncapping localizes to ruffling lamellae and rocketing vesicles | Supplementary information
Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers - pp980 - 986
Claudia Veigel, Justin E. Molloy, Stephan Schmitz & John Kendrick-Jones
doi:10.1038/ncb1060
First Paragraph - | Full Text - Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers | PDF (438 KB) - Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers
Discs-Large and Strabismus are functionally linked to plasma membrane formation - pp987 - 993
Ok-Kyung Lee, Kristopher K. Frese, Jennifer S. James, Darshana Chadda, Zhi-Hong Chen, Ronald T. Javier & Kyung-Ok Cho
doi:10.1038/ncb1055
First Paragraph - | Full Text - Discs-Large and Strabismus are functionally linked to plasma membrane formation | PDF (2,472 KB) - Discs-Large and Strabismus are functionally linked to plasma membrane formation | Supplementary information
The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila - pp994 - 1000
Michelle A. Li, Jeffrey D. Alls, Rita M. Avancini, Karen Koo & Dorothea Godt
doi:10.1038/ncb1058
First Paragraph - | Full Text - The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila | PDF (1,973 KB) - The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila | Supplementary information
See also: News and Views by McNeill
Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases - pp1001 - 1007
Manabu Furukawa, Yizhou Joseph He, Christoph Borchers & Yue Xiong
doi:10.1038/ncb1056
First Paragraph - | Full Text - Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases | PDF (354 KB) - Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases | Supplementary information
See also: News and Views by Krek
Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint - pp1008 - 1015
Leigh Ann A. Higa, Ivailo S. Mihaylov, Damon P. Banks, Jianyu Zheng & Hui Zhang
doi:10.1038/ncb1061
First Paragraph - | Full Text - Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint | PDF (550 KB) - Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint | Supplementary information
Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis - pp1016 - 1022
Moritoshi Sato, Yoshibumi Ueda, Tokio Takagi & Yoshio Umezawa
doi:10.1038/ncb1054
First Paragraph - | Full Text - Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis | PDF (459 KB) - Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis
Brief Communication
Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1 - pp1023 - 1025
Mary Herbert, Mark Levasseur, Hayden Homer, Katie Yallop, Alison Murdoch & Alex McDougall
doi:10.1038/ncb1062
Abstract - | Full Text - Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1 | PDF (288 KB) - Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1 | Supplementary information


