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Letter
Nature Cell Biology 5, 987–993 (1 November 2003) | doi:10.1038/ncb1055
Discs-Large and Strabismus are functionally linked to plasma membrane formation
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Abstract
During early embryogenesis in Drosophila melanogaster, extensive vesicle transport occurs to build cell boundaries for 6,000 nuclei. Here we show that this important process depends on a functional complex formed between the tumour suppressor and adaptor protein Discs-Large (Dlg) and the integral membrane protein Strabismus (Stbm)/Van Gogh (Vang).
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