Jemima Barrowman and Peter Novick are in the Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA. peter.novick@yale.edu
Rab GTPases function at all stages of the endocytic and exocytic pathways. Although it is clear that each Rab is required for specific transport events, the process by which they are recruited to distinct compartments along the membrane trafficking pathway has remained obscure. Recent data suggests that a member of the Yip family is important for the membrane recruitment of endosomal Rabs.
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